SCHEMBL20400663

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30401906	1.00	ADORA2B (0.42)	ADORA2BADORA2AADORA1PTGDRCYP19A1
	SCHEMBL20436653	0.91	ADORA2A (0.46)	ADORA2BADORA2AADORA1PTGDRCYP19A1
	SCHEMBL20416870	0.88	PTGDR (0.38)	ADORA2BADORA2AADORA1PTGDRCYP19A1
	SCHEMBL30401371	0.88	PTGDR (0.38)	ADORA2BADORA2AADORA1PTGDRCYP19A1
	SCHEMBL30401191	0.88	ADORA2A (0.39)	ADORA2BADORA2AADORA1PTGDRCYP19A1
	SCHEMBL20401313	0.88	ADORA2A (0.39)	ADORA2BADORA2AADORA1PTGDRCYP19A1
	SCHEMBL20401436	0.88	ADORA2A (0.41)	ADORA2BADORA2AADORA1HDAC6HDAC2
	SCHEMBL30401126	0.88	ADORA2A (0.41)	ADORA2BADORA2AADORA1HDAC6HDAC2
	SCHEMBL20401409	0.87	ADORA2A (0.38)	ADORA2BADORA2AADORA1PTGDRCYP19A1
	SCHEMBL20416742	0.87	CDC7 (0.43)	ADORA2BADORA2AADORA1PTGDRCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.