Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 7/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | IDH2 | P48735 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 2/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20400663 | 1.00 | ADORA2B (0.42) | ADORA2BADORA2AADORA1PTGDRCYP19A1 | |
| SCHEMBL20436653 | 0.91 | ADORA2A (0.46) | ADORA2BADORA2AADORA1PTGDRCYP19A1 | |
| SCHEMBL20416870 | 0.88 | PTGDR (0.38) | ADORA2BADORA2AADORA1PTGDRCYP19A1 | |
| SCHEMBL30401371 | 0.88 | PTGDR (0.38) | ADORA2BADORA2AADORA1PTGDRCYP19A1 | |
| SCHEMBL30401191 | 0.88 | ADORA2A (0.39) | ADORA2BADORA2AADORA1PTGDRCYP19A1 | |
| SCHEMBL20401313 | 0.88 | ADORA2A (0.39) | ADORA2BADORA2AADORA1PTGDRCYP19A1 | |
| SCHEMBL20401436 | 0.88 | ADORA2A (0.41) | ADORA2BADORA2AADORA1HDAC6HDAC2 | |
| SCHEMBL30401126 | 0.88 | ADORA2A (0.41) | ADORA2BADORA2AADORA1HDAC6HDAC2 | |
| SCHEMBL20401409 | 0.87 | ADORA2A (0.38) | ADORA2BADORA2AADORA1PTGDRCYP19A1 | |
| SCHEMBL20416742 | 0.87 | CDC7 (0.43) | ADORA2BADORA2AADORA1PTGDRCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768859-A | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-110214012-B | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-05-09 | — | — | CN | disclosed |