SCHEMBL20400745

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30401375	1.00	HTR7 (0.36)	HTR7PTGDRCYP19A1ADORA2AADORA2B
	SCHEMBL20436662	0.93	CYP19A1 (0.36)	HTR7PTGDRCYP19A1ADORA2AADORA2B
	SCHEMBL30401296	0.93	KDM4E (0.37)	PTGDRCYP19A1ADORA2AADORA2BADORA1
	SCHEMBL20416755	0.93	KDM4E (0.37)	PTGDRCYP19A1ADORA2AADORA2BADORA1
	SCHEMBL30401885	0.90	ADORA2B (0.38)	PTGDRCYP19A1ADORA2AADORA2BADORA1
	SCHEMBL20417125	0.90	ADORA2B (0.38)	PTGDRCYP19A1ADORA2AADORA2BADORA1
	SCHEMBL30400816	0.87	CDC7 (0.39)	ADORA2AADORA2BADORA1DYRK1ACLK4
	SCHEMBL20400630	0.87	CDC7 (0.39)	ADORA2AADORA2BADORA1DYRK1ACLK4
	SCHEMBL20416788	0.87	ADORA2A (0.36)	PTGDRCYP19A1ADORA2AADORA2BADORA1
	SCHEMBL30401452	0.87	ADORA2A (0.36)	PTGDRCYP19A1ADORA2AADORA2BADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.