Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10007248 | 0.72 | — | — | |
| SCHEMBL10007250 | 0.72 | — | — | |
| SCHEMBL20404154 | 0.70 | CES2 (0.34) | CES2 | |
| SCHEMBL10303794 | 0.60 | TSHR (0.30) | TSHR | |
| SCHEMBL10007577 | 0.60 | TSHR (0.30) | TSHR | |
| SCHEMBL14174369 | 0.59 | — | — | |
| SCHEMBL3303780 | 0.56 | CES2 (0.47) | CES2 | |
| SCHEMBL1361112 | 0.55 | MEN1 (0.44) | ALDH1A1 | |
| Alcohol SCHEMBL10550475 | 0.53 | CNR2 (0.39) | TSHR | |
| SCHEMBL21499078 | 0.53 | CNR2 (0.41) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3427738-B1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMA (US) | 2021-12-01 | — | — | EP | disclosed |
| EP-3427738-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | Vertex Pharmaceuticals Incorporated (US) | 2019-01-16 | — | — | EP | disclosed |
| EP-3141252-B1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMA (US) | 2018-07-25 | — | — | EP | disclosed |