SCHEMBL20405106

SCHEMBL20405106

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4ccccc4c3-c3cccc(-c4ccc5c6ccccc6c6ccccc6c5c4)c3)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.38
▸ ALDH1A1 P00352 4/20 0.38
▸ HPGD P15428 4/20 0.38
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ KDM4E B2RXH2 2/20 0.38
▸ ATM Q13315 2/20 0.38
▸ L3MBTL1 Q9Y468 2/20 0.38
▸ TP53 P04637 2/20 0.38
▸ MAPK1 P28482 2/20 0.38
▸ TSHR P16473 1/20 0.38
▸ NFKB1 P19838 1/20 0.38
▸ NFKB2 Q00653 1/20 0.38
▸ RELA Q04206 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ LMNA P02545 3/20 0.37
▸ NPC1 O15118 1/20 0.37
▸ RECQL P46063 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ CYP1A2 P05177 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18819329 0.96 MAPT (0.40) MAPTALDH1A1HPGDSMN1; SMN2KDM4E
SCHEMBL22639386 0.94 MAPT (0.38) MAPTALDH1A1HPGDSMN1; SMN2KDM4E
SCHEMBL22115008 0.94 MAPT (0.39) MAPTALDH1A1HPGDSMN1; SMN2KDM4E
SCHEMBL22639415 0.93 MAPT (0.38) MAPTALDH1A1HPGDSMN1; SMN2KDM4E
SCHEMBL22639498 0.93 MAPT (0.38) MAPTALDH1A1HPGDSMN1; SMN2KDM4E
SCHEMBL20405188 0.93 ESR1 (0.41) MAPTALDH1A1HPGDSMN1; SMN2KDM4E
SCHEMBL22639398 0.92 MAPT (0.37) MAPTALDH1A1HPGDSMN1; SMN2KDM4E
SCHEMBL22639408 0.92 MAPT (0.37) MAPTALDH1A1HPGDSMN1; SMN2KDM4E
SCHEMBL22639466 0.92 PDE7A (0.38) MAPTALDH1A1HPGDSMN1; SMN2KDM4E
SCHEMBL22639399 0.92 MAPT (0.37) MAPTALDH1A1HPGDSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11737357-B2 Compound and organic light-emitting device comprising same LG CHEM, LTD. 2023-08-22 — — US disclosed
US-11737357-B2 Compound and organic light-emitting device comprising same LG CHEM, LTD. 2023-08-22 — — US disclosed
US-20230255104-A1 Compound And Organic Light-Emitting Device Comprising Same LG CHEM, LTD. (KR) 2023-08-10 — — US disclosed
US-20230255104-A1 Compound And Organic Light-Emitting Device Comprising Same LG CHEM, LTD. (KR) 2023-08-10 — — US disclosed
EP-3351537-B1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2023-01-18 — — EP disclosed
EP-3351536-B1 ORGANIC LIGHT-EMITTING DEVICE LG CHEMICAL LTD (KR) 2021-07-21 — — EP disclosed
US-10367149-B2 Organic light-emitting device LG CHEM, LTD. (KR) 2019-07-30 — — US disclosed
US-20190055222-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2019-02-21 — — US disclosed
EP-3351537-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG Chem, Ltd. (KR) 2018-07-25 — — EP disclosed
EP-3351536-A1 ORGANIC LIGHT-EMITTING DEVICE LG Chem, Ltd. (KR) 2018-07-25 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11737357-B2 Compound and organic light-emitting device comprising same CRY1, CYP1B1, CYP1A1 MAPT 1315/4885ALDH1A1 11/4885HPGD 1649/4885
US-20230255104-A1 Compound And Organic Light-Emitting Device Comprising Same ARL1, AR, ALG3 MAPT 974/4885ALDH1A1 8/4885HPGD 3987/4885
US-10367149-B2 Organic light-emitting device CRY1, PPOX, CRY2 MAPT 774/4885ALDH1A1 91/4885HPGD 2330/4885
US-20190055222-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, CYP1B1, CYP1A1 MAPT 1315/4885ALDH1A1 11/4885HPGD 1649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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