Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 6/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | DDX3X | O00571 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20405679 | 0.90 | KCNN4 (0.32) | NPSR1ALDH1A1POLBKCNN4SMN1; SMN2 | |
| SCHEMBL20405685 | 0.81 | HPGD (0.37) | NPSR1KCNN4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2220115 | 0.78 | HTT (0.42) | NPSR1ALDH1A1POLBKCNN4SMN1; SMN2 | |
| SCHEMBL13765531 | 0.72 | IDH1 (0.35) | NPSR1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL13765502 | 0.71 | KCNN4 (0.33) | ALDH1A1KCNN4SMN1; SMN2LMNAMEN1 | |
| SCHEMBL2219573 | 0.70 | HTT (0.43) | NPSR1ALDH1A1POLBKCNN4SMN1; SMN2 | |
| SCHEMBL1423244 | 0.70 | REN (0.40) | NPSR1ALDH1A1POLBKCNN4SMN1; SMN2 | |
| SCHEMBL3456050 | 0.68 | KCNN4 (0.42) | NPSR1ALDH1A1KCNN4SMN1; SMN2 | |
| SCHEMBL20405636 | 0.66 | NPSR1 (0.37) | NPSR1ALDH1A1KCNN4SMN1; SMN2NPC1 | |
| SCHEMBL2217305 | 0.65 | HTT (0.46) | NPSR1ALDH1A1KCNN4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250165-B1 | TRIAZOLE OXADIAZOLES DERIVATIVES | MERCK SERONO SA (CH) | 2018-07-25 | — | — | EP | disclosed |