Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13765531 | 0.83 | IDH1 (0.35) | HPGDL3MBTL1TSHRSMN1; SMN2TP53 | |
| SCHEMBL20405705 | 0.81 | NPSR1 (0.35) | TSHRSMN1; SMN2LMNAKCNN4NPC1 | |
| SCHEMBL20405679 | 0.75 | KCNN4 (0.32) | TSHRSMN1; SMN2LMNAKCNN4NPSR1 | |
| SCHEMBL3456050 | 0.73 | KCNN4 (0.42) | SMN1; SMN2TP53KCNN4NPSR1MET | |
| SCHEMBL3766923 | 0.69 | PPARA (0.44) | HPGDTSHRSMN1; SMN2TP53HSD17B10 | |
| SCHEMBL20405823 | 0.68 | KCNN4 (0.42) | TSHRKCNN4SCN9A | |
| SCHEMBL13765502 | 0.68 | KCNN4 (0.33) | SMN1; SMN2LMNAKCNN4KMT2AMEN1 | |
| SCHEMBL1423244 | 0.67 | REN (0.40) | SMN1; SMN2LMNAKCNN4NPSR1KMT2A | |
| SCHEMBL10180279 | 0.63 | RAB9A (0.46) | SMN1; SMN2TP53HSD17B10LMNANPC1 | |
| SCHEMBL28034285 | 0.62 | REN (0.39) | SMN1; SMN2LMNAKCNN4NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250165-B1 | TRIAZOLE OXADIAZOLES DERIVATIVES | MERCK SERONO SA (CH) | 2018-07-25 | — | — | EP | disclosed |