Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20394174 | 0.87 | PDE10A (0.47) | GRM2CYSLTR1MAPTPDE10A | |
| SCHEMBL20406528 | 0.76 | PDE10A (0.37) | GRM2CYSLTR1MAPTL3MBTL1PDE10A | |
| SCHEMBL20394360 | 0.76 | PDE10A (0.45) | PDE10A | |
| SCHEMBL20406527 | 0.75 | GAA (0.39) | GRM2CYSLTR1MAPTL3MBTL1PDE10A | |
| SCHEMBL20406415 | 0.73 | AHR (0.39) | MAPTPDE10AMEN1KMT2A | |
| SCHEMBL20406760 | 0.73 | PDE10A (0.40) | GRM2CYSLTR1MAPTL3MBTL1PDE10A | |
| SCHEMBL20406654 | 0.72 | RORC (0.44) | MAPTPDE10AMEN1KMT2ARORC | |
| SCHEMBL20394285 | 0.72 | PDE10A (0.52) | GRM2CYSLTR1PDE10AKMT2A | |
| SCHEMBL20406230 | 0.72 | MEN1 (0.37) | MAPTL3MBTL1PDE10AMEN1KMT2A | |
| SCHEMBL20394394 | 0.72 | PDE10A (0.44) | PDE10AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |