Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20406262 | 0.87 | PDE10A (0.42) | PDE10AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL20406219 | 0.85 | PDE10A (0.46) | PDE10AALDH1A1MAPTATM | |
| SCHEMBL20406303 | 0.83 | MEN1 (0.46) | PDE10AMEN1KMT2ADRD1 | |
| SCHEMBL20406169 | 0.83 | PDE10A (0.39) | PDE10AMEN1KMT2ASCN9AALDH1A1 | |
| SCHEMBL20406196 | 0.81 | PDE10A (0.43) | PDE10AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL20394384 | 0.80 | PDE10A (0.45) | PDE10AMEN1KMT2A | |
| SCHEMBL20406394 | 0.80 | MEN1 (0.33) | PDE10AMEN1KMT2ADRD1 | |
| SCHEMBL20406318 | 0.80 | ICAM1 (0.38) | SCN9AALDH1A1 | |
| SCHEMBL20406261 | 0.78 | MEN1 (0.38) | MEN1KMT2ASCN9AALDH1A1DRD1 | |
| SCHEMBL4008297 | 0.78 | PDE10A (0.45) | PDE10ASCN9AALDH1A1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |