Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20406602 | 0.85 | PDE10A (0.40) | MEN1KMT2APDE10ADRD1TDP1 | |
| SCHEMBL20406293 | 0.83 | PDE10A (0.44) | MEN1KMT2APDE10ADRD1 | |
| SCHEMBL20406196 | 0.81 | PDE10A (0.43) | MEN1KMT2APDE10ADRD1GCK | |
| SCHEMBL20406219 | 0.79 | PDE10A (0.46) | PDE10A | |
| SCHEMBL20406612 | 0.79 | PDE10A (0.48) | MEN1KMT2APDE10ADRD1TDP1 | |
| SCHEMBL20406603 | 0.77 | PDE10A (0.46) | PDE10ADRD1TDP1GAA | |
| SCHEMBL20406262 | 0.76 | PDE10A (0.42) | MEN1KMT2APDE10ADRD1 | |
| SCHEMBL20406610 | 0.76 | PDE10A (0.51) | MEN1KMT2APDE10ADRD1TDP1 | |
| SCHEMBL31395507 | 0.76 | PDE10A (0.51) | MEN1KMT2APDE10ADRD1TDP1 | |
| SCHEMBL7910614 | 0.76 | KMT2A (0.59) | MEN1KMT2APDE10ADRD1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |