Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 3/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20406320 | 0.86 | EGFR (0.32) | EGFRFLT3KDRSMN1; SMN2THRB | |
| SCHEMBL20406664 | 0.84 | CSF1R (0.34) | SCN9A | |
| SCHEMBL20406321 | 0.82 | ALDH1A1 (0.36) | EGFRFLT3KDRSMN1; SMN2ALDH1A1 | |
| SCHEMBL20406293 | 0.80 | PDE10A (0.44) | ALDH1A1SCN9A | |
| SCHEMBL31395363 | 0.76 | TRPA1 (0.49) | EGFRFLT3KDRSMN1; SMN2ALDH1A1 | |
| SCHEMBL20406319 | 0.73 | APP (0.35) | ICAM1SELEEGFRFLT3KDR | |
| SCHEMBL20406261 | 0.72 | MEN1 (0.38) | ICAM1SELEVCAM1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20406662 | 0.71 | TRPA1 (0.33) | EGFRKDRSMN1; SMN2SCN9ALMNA | |
| SCHEMBL21501176 | 0.68 | LTA4H (0.52) | — | |
| SCHEMBL20406228 | 0.67 | EGFR (0.42) | EGFRFLT3KDRSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |