Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13331058 | 0.79 | PDE10A (0.56) | PDE10ATDP1KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL20406196 | 0.78 | PDE10A (0.43) | PDE10ADRD1ALDH1A1 | |
| SCHEMBL20406303 | 0.77 | MEN1 (0.46) | PDE10ATDP1DRD1GAA | |
| SCHEMBL20406602 | 0.76 | PDE10A (0.40) | PDE10ATDP1DRD1ALDH1A1RAB9A | |
| SCHEMBL20406219 | 0.76 | PDE10A (0.46) | PDE10AALDH1A1 | |
| SCHEMBL20406612 | 0.76 | PDE10A (0.48) | PDE10ATDP1KDM4EL3MBTL1DRD1 | |
| SCHEMBL20406605 | 0.75 | LMNA (0.49) | PDE10ATDP1KDM4EL3MBTL1GAA | |
| SCHEMBL20406531 | 0.75 | PDE10A (0.58) | PDE10ATDP1KDM4EL3MBTL1DRD1 | |
| SCHEMBL31254676 | 0.75 | PLCG1 (0.51) | TDP1PLCG1KDM4EL3MBTL1GAA | |
| SCHEMBL3191632 | 0.74 | SMN1; SMN2 (0.51) | L3MBTL1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |