Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.37 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.37 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.37 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20406254 | 0.91 | PDE10A (0.46) | PDE10AMEN1KMT2ADRD1ALDH1A1 | |
| SCHEMBL20406212 | 0.82 | PDE10A (0.43) | PDE10AMEN1KMT2ADRD1ALDH1A1 | |
| SCHEMBL20406367 | 0.80 | PDE10A (0.46) | LTA4HEPHX2PDE10AMEN1KMT2A | |
| SCHEMBL20406089 | 0.79 | L3MBTL1 (0.49) | PDE10AMEN1KMT2ADRD1ALDH1A1 | |
| SCHEMBL20406289 | 0.78 | PDE10A (0.40) | LTA4HPDE10AMEN1KMT2ADRD1 | |
| SCHEMBL20406378 | 0.78 | PDE10A (0.46) | PDE10AMAPTL3MBTL1 | |
| SCHEMBL20406610 | 0.77 | PDE10A (0.51) | LTA4HPDE10AMEN1KMT2ADRD1 | |
| SCHEMBL31395507 | 0.77 | PDE10A (0.51) | LTA4HPDE10AMEN1KMT2ADRD1 | |
| SCHEMBL24553667 | 0.75 | NPC1 (0.41) | PDE10AMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL4008329 | 0.74 | PDE10A (0.51) | LTA4HPDE10AMEN1KMT2ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |