SCHEMBL4008329

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3878940	0.85	PDE10A (0.43)	PDE10ATDP1ALDH1A1KMT2AMEN1
	SCHEMBL20406612	0.83	PDE10A (0.48)	PDE10ATDP1ALDH1A1KMT2AMEN1
	SCHEMBL580112	0.83	MEN1 (0.56)	PDE10ATDP1ALDH1A1KMT2AMEN1
	SCHEMBL31395507	0.83	PDE10A (0.51)	PDE10ATDP1KMT2AMEN1LTA4H
	SCHEMBL20406610	0.83	PDE10A (0.51)	PDE10ATDP1KMT2AMEN1LTA4H
	SCHEMBL20406238	0.83	PDE10A (0.48)	PDE10ATDP1ALDH1A1KMT2AMEN1
	SCHEMBL7910614	0.83	KMT2A (0.59)	PDE10ATDP1ALDH1A1KMT2AMEN1
	SCHEMBL2488534	0.83	RAB9A (0.56)	PDE10AALDH1A1KMT2AMEN1CYP1A2
	SCHEMBL15923259	0.83	LMNA (0.52)	PDE10ATDP1ALDH1A1LTA4HPOLB
	SCHEMBL31395515	0.83	PDE10A (0.53)	PDE10AKMT2ACYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.