Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 8/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20406682 | 0.83 | STK4 (0.47) | CNR2PDE10APIK3CAMTOR | |
| SCHEMBL20406479 | 0.80 | MEN1 (0.35) | ELANE | |
| SCHEMBL20406637 | 0.71 | MAPK8 (0.35) | ELANE | |
| SCHEMBL3880853 | 0.71 | ALDH1A1 (0.50) | PIK3CAMTOR | |
| SCHEMBL18661502 | 0.70 | PDE10A (0.39) | PDE10A | |
| SCHEMBL20406447 | 0.69 | ACACB (0.46) | — | |
| SCHEMBL13409587 | 0.69 | CYP1A2 (0.56) | ELANEPOLBPIK3CA | |
| SCHEMBL10414486 | 0.68 | SMN1; SMN2 (0.58) | POLB | |
| SCHEMBL8116304 | 0.68 | BTK (0.49) | PDE10AELANE | |
| SCHEMBL20406475 | 0.67 | KMT2A (0.40) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |