Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | AOC2 | O75106 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20394481 | 0.87 | CYP2D6 (0.42) | MEN1KMT2A | |
| SCHEMBL20406475 | 0.81 | KMT2A (0.40) | MEN1KMT2AP2RY1 | |
| SCHEMBL18661502 | 0.81 | PDE10A (0.39) | MEN1KMT2ASCN9ALIPE | |
| SCHEMBL20406684 | 0.80 | AOC3 (0.41) | ELANE | |
| SCHEMBL20406442 | 0.77 | RORC (0.32) | MEN1KMT2AELANEP2RY1 | |
| SCHEMBL20406690 | 0.73 | PDE10A (0.38) | MEN1KMT2ASCN9ALIPE | |
| SCHEMBL20394318 | 0.71 | PDE10A (0.38) | MEN1KMT2ASCN9ALIPE | |
| SCHEMBL20406375 | 0.71 | P2RY1 (0.39) | P2RY1KCNH2 | |
| SCHEMBL20406391 | 0.71 | MEN1 (0.46) | MEN1KMT2ASCN9AP2RY1LIPE | |
| SCHEMBL18661344 | 0.70 | PDE10A (0.39) | KMT2AELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |