Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | TNKS | O95271 | 2/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17256119 | 0.91 | GPR84 (0.40) | GPR84HSD17B2HSP90AA1HSP90AB1PTGES | |
| SCHEMBL15865044 | 0.85 | HSD17B10 (0.36) | GPR84ALOX5MEN1KMT2APOLB | |
| SCHEMBL15870859 | 0.81 | HPGD (0.37) | GPR84ALOX5MEN1KMT2APOLB | |
| SCHEMBL17264192 | 0.75 | GPR84 (0.41) | GPR84HSD17B2HSP90AA1HSP90AB1PTGES | |
| SCHEMBL17264195 | 0.74 | KCNJ11 (0.34) | ALOX5POLBGAACYP2D6HPGD | |
| SCHEMBL2132427 | 0.73 | CYP2C9 (0.42) | GPR84HSD17B2ALOX5SMN1; SMN2MEN1 | |
| SCHEMBL14063310 | 0.72 | HSD17B10 (0.45) | MEN1KMT2APOLBGAACYP2D6 | |
| SCHEMBL15870967 | 0.72 | MEN1 (0.44) | GPR84HSD17B2HSP90AA1HSP90AB1MEN1 | |
| SCHEMBL15870870 | 0.70 | MEN1 (0.43) | TP53SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL10063930 | 0.68 | TP53 (0.43) | GPR84PTGESALOX5TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2941472-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-07-25 | — | — | EP | disclosed |