Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15865044 | 0.96 | HSD17B10 (0.36) | HPGDHSD17B10CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL2132427 | 0.91 | CYP2C9 (0.42) | HPGDHSD17B10CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL17256119 | 0.89 | GPR84 (0.40) | HPGDHSD17B10CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL14063310 | 0.88 | HSD17B10 (0.45) | HPGDHSD17B10CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL17264195 | 0.84 | KCNJ11 (0.34) | HPGDCYP2C9CYP1A2CYP2D6MAPT | |
| SCHEMBL20407302 | 0.81 | GPR84 (0.37) | HPGDHSD17B10CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL15870870 | 0.80 | MEN1 (0.43) | HPGDHSD17B10CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL12671792 | 0.77 | MAPT (0.34) | HPGDHSD17B10CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL13152865 | 0.77 | ALOX5 (0.42) | HPGDHSD17B10CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL24803603 | 0.76 | GPR84 (0.40) | HPGDHSD17B10CYP2C19CYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2941472-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-07-25 | — | — | EP | disclosed |
| US-20150329772-A1 | Materials for Electronic Devices | MERCK PATENT GMBH (DE) | 2015-11-19 | — | — | US | disclosed |
| US-20150329772-A1 | Materials for Electronic Devices | MERCK PATENT GMBH (DE) | 2015-11-19 | — | — | US | disclosed |
| WO-2014106522-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2014-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329772-A1 | Materials for Electronic Devices | EFNA1, SDHB, ETFA | HPGD 942/4885HSD17B10 3025/4885CYP2C19 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.