Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17264194 | 0.87 | WDR5 (0.47) | GPR84WDR5PTGESALOX5HPGD | |
| SCHEMBL15870967 | 0.87 | MEN1 (0.44) | GPR84WDR5HSD17B2HSP90AA1HSP90AB1 | |
| SCHEMBL17264193 | 0.80 | MCL1 (0.38) | WDR5HPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL17256119 | 0.80 | GPR84 (0.40) | GPR84HSD17B2PTGESALOX5HSP90AA1 | |
| SCHEMBL17070768 | 0.78 | WDR5 (0.59) | WDR5HPGDMEN1KMT2AMAOB | |
| SCHEMBL17255965 | 0.76 | MAPT (0.50) | GPR84WDR5HPGDMEN1KMT2A | |
| SCHEMBL17264189 | 0.76 | WDR5 (0.49) | WDR5HPGDMEN1KMT2AMAOB | |
| SCHEMBL20407302 | 0.75 | GPR84 (0.37) | GPR84HSD17B2PTGESALOX5HSP90AA1 | |
| SCHEMBL15870974 | 0.73 | MAPT (0.47) | GPR84WDR5HPGDMEN1KMT2A | |
| SCHEMBL10063930 | 0.73 | TP53 (0.43) | GPR84PTGESALOX5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150329772-A1 | Materials for Electronic Devices | MERCK PATENT GMBH (DE) | 2015-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329772-A1 | Materials for Electronic Devices | EFNA1, SDHB, ETFA | GPR84 4139/4885WDR5 4233/4885HSD17B2 1839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.