Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14134529 | 0.80 | MAPT (0.56) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL15870967 | 0.80 | MEN1 (0.44) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL17255965 | 0.80 | MAPT (0.50) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30356865 | 0.77 | MAPT (0.61) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL593520 | 0.77 | MAPT (0.61) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL16384877 | 0.77 | SLC6A3 (0.62) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL15870974 | 0.77 | MAPT (0.47) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13152864 | 0.76 | SLC6A3 (0.57) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL12130324 | 0.75 | ALOX5 (0.44) | — | |
| SCHEMBL17304516 | 0.74 | MAPT (0.55) | MAPTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2941472-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-07-25 | — | — | EP | disclosed |