SCHEMBL20407459

SCHEMBL20407459

C=C(C)C1CCC(C2CCCCC2)CC1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
LMNA P02545 1/20 0.33
HSD11B1 P28845 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
ALOX15 P16050 1/20 0.31
CYP1B1 Q16678 1/20 0.31
SLC18A3 Q16572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4359650 0.84 CES2 (0.43) ALDH1A1LMNAHSD11B1CES2CES1
SCHEMBL307206 0.84
Methane SCHEMBL27789915 0.81 CES2 (0.41) ALDH1A1LMNAHSD11B1CES2CES1
SCHEMBL1437686 0.81
SCHEMBL11103446 0.81 LMNA (0.42) ALDH1A1LMNAALOX15CYP1B1
SCHEMBL9129884 0.81
SCHEMBL513994 0.81
SCHEMBL12158779 0.80 LMNA (0.33) ALDH1A1LMNAALOX15CYP1B1
SCHEMBL28121576 0.79 ALDH1A1 (0.35) ALDH1A1LMNAHSD11B1CES2CES1
SCHEMBL27813655 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3351525-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2018-07-25 EP disclosed