Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.49 |
| ▸ | CPB1 | P15086 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211761 | 0.78 | CPB2 (0.47) | CPB2CPB1TSHRHRH4HRH3 | |
| SCHEMBL6647530 | 0.77 | CPB2 (0.50) | CPB2CPB1GBA1KDM4CCHRM2 | |
| SCHEMBL20389632 | 0.76 | CXCR4 (0.43) | CPB2CPB1TSHRCYP2C9CYP2C19 | |
| SCHEMBL11000404 | 0.73 | HRH4 (0.43) | CPB2CPB1HRH4HRH3KDM4C | |
| SCHEMBL22783610 | 0.73 | CYP2C9 (0.62) | CPB2CPB1TSHRCYP2C9CYP2C19 | |
| SCHEMBL15020818 | 0.72 | CPB2 (0.54) | CPB2CPB1TSHRCYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL9803226 | 0.71 | TDP1 (0.63) | CPB2CPB1TSHRCYP2C9CYP2C19 | |
| SCHEMBL1789627 | 0.70 | CYP2C9 (0.58) | CPB2CPB1TSHRCYP2C9CYP2C19 | |
| SCHEMBL1787076 | 0.69 | CYP2C9 (0.56) | CPB2CPB1TSHRCYP2C9CYP2C19 | |
| SCHEMBL28704555 | 0.69 | CYP2C9 (0.56) | CPB2CPB1TSHRCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180208588-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | NATIONAL HEALTH RES INST (TW) | 2018-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180208588-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | CXCL12, HPGDS, CX3CR1 | CPB2 1575/4885CPB1 2228/4885SIGMAR1 4325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.