Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 7/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8737612 | 0.87 | RIPK1 (0.41) | KDM4EALDH1A1RIPK1POLBELANE | |
| SCHEMBL15179699 | 0.84 | RIPK1 (0.39) | KDM4ERIPK1ELANE | |
| SCHEMBL20408449 | 0.84 | RIPK1 (0.39) | KDM4EALDH1A1SMN1; SMN2RIPK1ELANE | |
| SCHEMBL12419165 | 0.83 | RIPK1 (0.43) | KDM4EALDH1A1RIPK1CYP1A2ELANE | |
| SCHEMBL15179685 | 0.82 | RIPK1 (0.37) | KDM4ESMN1; SMN2RIPK1CYP1A2ELANE | |
| SCHEMBL18135088 | 0.79 | HPGDS (0.48) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9IDO1 | |
| SCHEMBL12385767 | 0.79 | HDAC3 (0.35) | KDM4EALDH1A1SMN1; SMN2RIPK1CYP1A2 | |
| SCHEMBL15447048 | 0.78 | LMNA (0.45) | ALDH1A1MAPK1SMN1; SMN2RIPK1ELANE | |
| SCHEMBL17109940 | 0.78 | CYP1A2 (0.37) | KDM4EALDH1A1SMN1; SMN2RIPK1CYP1A2 | |
| SCHEMBL16672587 | 0.77 | POLB (0.46) | ALDH1A1SMN1; SMN2POLBELANELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180210338-A1 | RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN | TOKYO OHKA KOGYO CO., LTD. (JP) | 2018-07-26 | — | — | US | disclosed |