SCHEMBL20409662

SCHEMBL20409662

CC1(C)COC(c2ccc(-c3c4ccccc4c(-c4cccc5ccccc45)c4ccccc34)cn2)=N1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.48
EED O75530 1/20 0.39
SUZ12 Q15022 1/20 0.39
EZH2 Q15910 1/20 0.39
ENPP1 P22413 2/20 0.35
ENPP3 O14638 1/20 0.35
MAPT P10636 2/20 0.34
DHFR P00374 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HRH3 Q9Y5N1 3/20 0.33
CYP2D6 P10635 1/20 0.33
MAPK3 P27361 1/20 0.33
MAPK1 P28482 1/20 0.33
PTPN11 Q06124 1/20 0.33
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20409959 0.89 KDM4E (0.51) KDM4EEEDSUZ12EZH2MAPT
SCHEMBL20409653 0.86 KDM4E (0.48) KDM4EENPP1ENPP3MAPTDHFR
SCHEMBL20410548 0.86 KDM4E (0.44) KDM4EEEDSUZ12EZH2MAPT
SCHEMBL20409617 0.85 KDM4E (0.46) KDM4EEEDSUZ12EZH2MAPT
SCHEMBL20409665 0.83 ENPP1 (0.36) KDM4EENPP1ENPP3MAPTDHFR
SCHEMBL20410560 0.82 KDM4E (0.47) KDM4EEEDSUZ12EZH2MAPT
SCHEMBL20409671 0.82 KDM4E (0.65) KDM4EENPP1ENPP3MAPTDHFR
SCHEMBL20409644 0.81 KDM4E (0.46) KDM4EMAPTDHFRNPC1RAB9A
SCHEMBL29511679 0.81 KDM4E (0.43) KDM4EEEDSUZ12EZH2MAPT
SCHEMBL20409593 0.81 KDM4E (0.43) KDM4EEEDSUZ12EZH2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11342511-B2 Azoline ring-containing compound, electron transport/injection layer material containing the same, and organic electroluminescent element using the same SK MATERIALS JNC CO., LTD. (KR) 2022-05-24 US disclosed
US-20180212156-A1 AZOLINE RING-CONTAINING COMPOUND, ELECTRON TRANSPORT/INJECTION LAYER MATERIAL CONTAINING THE SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME JNC CORPORATION (JP) 2018-07-26 US disclosed
US-20180212156-A1 AZOLINE RING-CONTAINING COMPOUND, ELECTRON TRANSPORT/INJECTION LAYER MATERIAL CONTAINING THE SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME JNC CORPORATION (JP) 2018-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11342511-B2 Azoline ring-containing compound, electron transport/injection layer material containing the same, and organic electroluminescent element using the same SLC7A5, EML4, ARNT KDM4E 776/4885EED 393/4885SUZ12 1568/4885
US-20180212156-A1 AZOLINE RING-CONTAINING COMPOUND, ELECTRON TRANSPORT/INJECTION LAYER MATERIAL CONTAINING THE SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME SLC7A5, EML4, ARNT KDM4E 776/4885EED 393/4885SUZ12 1568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.