Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SGK1 | O00141 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29511679 | 1.00 | KDM4E (0.43) | KDM4EHRH3EEDSUZ12EZH2 | |
| SCHEMBL20409919 | 0.93 | KDM4E (0.42) | KDM4EHRH3EEDSUZ12EZH2 | |
| SCHEMBL20409959 | 0.91 | KDM4E (0.51) | KDM4EHRH3EEDSUZ12EZH2 | |
| SCHEMBL20409720 | 0.87 | KDM4E (0.42) | KDM4EHRH3EEDSUZ12EZH2 | |
| SCHEMBL20410312 | 0.87 | KDM4E (0.48) | KDM4EHRH3EEDSUZ12EZH2 | |
| SCHEMBL20396075 | 0.86 | KDM4E (0.42) | KDM4EHRH3LMNAHTTMAPT | |
| SCHEMBL20410592 | 0.84 | KDM4E (0.50) | KDM4EHRH3EEDSUZ12EZH2 | |
| SCHEMBL20409968 | 0.84 | KDM4E (0.49) | KDM4EHRH3EEDSUZ12EZH2 | |
| SCHEMBL20409617 | 0.84 | KDM4E (0.46) | KDM4EHRH3EEDSUZ12EZH2 | |
| SCHEMBL20410560 | 0.83 | KDM4E (0.47) | KDM4EHRH3EEDSUZ12EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11877506-B2 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2024-01-16 | — | — | US | disclosed |
| US-11877506-B2 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2024-01-16 | — | — | US | disclosed |
| US-20230276708-A1 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2023-08-31 | — | — | US | disclosed |
| US-20230276708-A1 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2023-08-31 | — | — | US | disclosed |
| US-11342511-B2 | Azoline ring-containing compound, electron transport/injection layer material containing the same, and organic electroluminescent element using the same | SK MATERIALS JNC CO., LTD. (KR) | 2022-05-24 | — | — | US | disclosed |
| US-20180212156-A1 | AZOLINE RING-CONTAINING COMPOUND, ELECTRON TRANSPORT/INJECTION LAYER MATERIAL CONTAINING THE SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME | JNC CORPORATION (JP) | 2018-07-26 | — | — | US | disclosed |
| US-20180212156-A1 | AZOLINE RING-CONTAINING COMPOUND, ELECTRON TRANSPORT/INJECTION LAYER MATERIAL CONTAINING THE SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME | JNC CORPORATION (JP) | 2018-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11877506-B2 | Polycyclic aromatic compound | F11, C1R, RNF31 | KDM4E 4253/4885HRH3 465/4885EED 2892/4885 |
| US-20230276708-A1 | Polycyclic aromatic compound | ACVR1B, XDH, AHR | KDM4E 583/4885HRH3 931/4885EED 92/4885 |
| US-11342511-B2 | Azoline ring-containing compound, electron transport/injection layer material containing the same, and organic electroluminescent element using the same | SLC7A5, EML4, ARNT | KDM4E 776/4885HRH3 1096/4885EED 393/4885 |
| US-20180212156-A1 | AZOLINE RING-CONTAINING COMPOUND, ELECTRON TRANSPORT/INJECTION LAYER MATERIAL CONTAINING THE SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME | SLC7A5, EML4, ARNT | KDM4E 776/4885HRH3 1096/4885EED 393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.