SCHEMBL20410312

SCHEMBL20410312

CC1(C)COC(c2ccc(-c3ccc4c5ccc(-c6ccc(C7=NC(C)(C)CO7)nc6)cc5c5ccccc5c4c3)cn2)=N1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.48
EED O75530 1/20 0.38
SUZ12 Q15022 1/20 0.38
EZH2 Q15910 1/20 0.38
HTT P42858 2/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
HRH3 Q9Y5N1 4/20 0.37
CYP2D6 P10635 1/20 0.37
ATM Q13315 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33
IL2 P60568 1/20 0.32
S1PR3 Q99500 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20410295 0.90 KDM4E (0.44) KDM4EEEDSUZ12EZH2HTT
SCHEMBL29511679 0.87 KDM4E (0.43) KDM4EEEDSUZ12EZH2HTT
SCHEMBL20409593 0.87 KDM4E (0.43) KDM4EEEDSUZ12EZH2HTT
SCHEMBL20409720 0.85 KDM4E (0.42) KDM4EEEDSUZ12EZH2HTT
SCHEMBL20409959 0.85 KDM4E (0.51) KDM4EEEDSUZ12EZH2HTT
SCHEMBL20410863 0.85 KDM4E (0.53) KDM4EEEDSUZ12EZH2HTT
SCHEMBL20410592 0.84 KDM4E (0.50) KDM4EEEDSUZ12EZH2HTT
SCHEMBL20409919 0.84 KDM4E (0.42) KDM4EEEDSUZ12EZH2HTT
SCHEMBL20409592 0.84 KDM4E (0.47) KDM4EHTTLMNAMAPTHRH3
SCHEMBL20410515 0.84 KDM4E (0.47) KDM4EEEDSUZ12EZH2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11342511-B2 Azoline ring-containing compound, electron transport/injection layer material containing the same, and organic electroluminescent element using the same SK MATERIALS JNC CO., LTD. (KR) 2022-05-24 US disclosed
US-20180212156-A1 AZOLINE RING-CONTAINING COMPOUND, ELECTRON TRANSPORT/INJECTION LAYER MATERIAL CONTAINING THE SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME JNC CORPORATION (JP) 2018-07-26 US disclosed
US-20180212156-A1 AZOLINE RING-CONTAINING COMPOUND, ELECTRON TRANSPORT/INJECTION LAYER MATERIAL CONTAINING THE SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME JNC CORPORATION (JP) 2018-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11342511-B2 Azoline ring-containing compound, electron transport/injection layer material containing the same, and organic electroluminescent element using the same SLC7A5, EML4, ARNT KDM4E 776/4885EED 393/4885SUZ12 1568/4885
US-20180212156-A1 AZOLINE RING-CONTAINING COMPOUND, ELECTRON TRANSPORT/INJECTION LAYER MATERIAL CONTAINING THE SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME SLC7A5, EML4, ARNT KDM4E 776/4885EED 393/4885SUZ12 1568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.