Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2422488 | 0.87 | RORC (0.41) | GPR119USP2SMN1; SMN2STSRORC | |
| SCHEMBL25541363 | 0.80 | USP2 (0.45) | GPR119USP2SMN1; SMN2 | |
| SCHEMBL25528784 | 0.80 | USP2 (0.45) | GPR119USP2SMN1; SMN2 | |
| SCHEMBL20396140 | 0.77 | USP2 (0.42) | GPR119USP2SMN1; SMN2 | |
| SCHEMBL20395925 | 0.77 | USP2 (0.39) | GPR119USP2SMN1; SMN2STSRORC | |
| SCHEMBL24753745 | 0.76 | GPR119 (0.43) | GPR119USP2SMN1; SMN2STS | |
| SCHEMBL19839770 | 0.74 | SCD5 (0.47) | GPR119 | |
| SCHEMBL10257892 | 0.73 | GPR119 (0.42) | GPR119 | |
| SCHEMBL20396153 | 0.73 | USP30 (0.40) | GPR119USP2SMN1; SMN2 | |
| SCHEMBL12262223 | 0.71 | GPR119 (0.44) | GPR119RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180208607-A1 | 1,1,1-TRIFLUORO-3-HYDROXYPROPAN-2-YL CARBAMATE DERIVATIVES AS MAGL INHIBITORS | PFIZER INC. (US) | 2018-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180208607-A1 | 1,1,1-TRIFLUORO-3-HYDROXYPROPAN-2-YL CARBAMATE DERIVATIVES AS MAGL INHIBITORS | MAG, PYM1, HIF1AN | GPR119 748/4885USP2 4400/4885SMN1; SMN2 1148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.