Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20413179 | 0.90 | KDM4E (0.41) | KDM4EATML3MBTL1DHFRCLK4 | |
| SCHEMBL19269303 | 0.89 | KDM4E (0.36) | KDM4EATML3MBTL1CLK4DYRK1A | |
| SCHEMBL9955519 | 0.88 | HTR1A (0.43) | KDM4EATML3MBTL1DHFRPTGER1 | |
| SCHEMBL12691250 | 0.88 | KDM4E (0.41) | KDM4EATML3MBTL1MEN1GAA | |
| SCHEMBL21365889 | 0.88 | L3MBTL1 (0.45) | KDM4EATML3MBTL1MEN1GAA | |
| SCHEMBL21647268 | 0.87 | L3MBTL1 (0.50) | KDM4EATML3MBTL1DHFRCLK4 | |
| SCHEMBL17878985 | 0.86 | L3MBTL1 (0.44) | KDM4EATML3MBTL1MEN1GAA | |
| SCHEMBL12691170 | 0.86 | L3MBTL1 (0.44) | KDM4EATML3MBTL1MEN1GAA | |
| SCHEMBL12690809 | 0.86 | L3MBTL1 (0.44) | KDM4EATML3MBTL1MEN1GAA | |
| SCHEMBL12456569 | 0.86 | L3MBTL1 (0.44) | KDM4EATML3MBTL1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180212158-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2018-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180212158-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | MSN, DDT, NECTIN4 | KDM4E 2444/4885ATM 3591/4885L3MBTL1 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.