Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 12/20 | 0.57 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.48 |
| ▸ | SPR | P35270 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17981221 | 0.90 | NR3C1 (0.56) | NR3C1PDE7A | |
| SCHEMBL20413595 | 0.78 | NR3C1 (0.89) | NR3C1 | |
| SCHEMBL20413616 | 0.78 | SPR (0.59) | NR3C1SPRRAB9ASMN1; SMN2 | |
| SCHEMBL17963365 | 0.73 | NR3C1 (1.00) | NR3C1 | |
| SCHEMBL17963218 | 0.71 | NR3C1 (1.00) | NR3C1 | |
| SCHEMBL17981252 | 0.71 | NR3C1 (0.84) | NR3C1 | |
| SCHEMBL20413502 | 0.70 | NR3C1 (0.88) | NR3C1 | |
| SCHEMBL17980518 | 0.70 | NR3C1 (0.71) | NR3C1SPRRAB9A | |
| SCHEMBL20413598 | 0.69 | RAB9A (0.53) | NR3C1RAB9ASMN1; SMN2 | |
| SCHEMBL17963352 | 0.69 | SPR (0.53) | NR3C1PDE7ASPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180207140-A1 | Pyrazolopyrimidines as Inhibitors of Glucocorticoid Receptor Translocation | Sanford Burnham Prebys Medical Discovery Institute | 2018-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180207140-A1 | Pyrazolopyrimidines as Inhibitors of Glucocorticoid Receptor Translocation | NR3C1, NR3C2, GRK3 | NR3C1 1/4885PDE7A 368/4885SPR 2583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.