Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.66 |
| ▸ | HTR3B | O95264 | 1/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.66 |
| ▸ | HTR3A | P46098 | 1/20 | 0.66 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.66 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107369 | 1.00 | HTR3E (0.66) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| SCHEMBL20748280 | 1.00 | HTR3E (0.66) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| SCHEMBL20415006 | 1.00 | HTR3E (0.66) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| SCHEMBL2925759 | 0.98 | HTR3E (0.68) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| SCHEMBL28599511 | 0.89 | HTR3E (0.73) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| SCHEMBL29656856 | 0.89 | HTR3E (0.73) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| SCHEMBL18409051 | 0.87 | HTR3E (0.56) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| SCHEMBL9658356 | 0.87 | HTR3E (0.56) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| SCHEMBL10769390 | 0.87 | HTR3E (0.56) | HTR3EHTR3BADRB1HTR3AHTR3D | |
| SCHEMBL31164294 | 0.86 | MAPT (0.68) | MAPTRAB9AKMT2AALDH1A1NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180207628-A1 | OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2018-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180207628-A1 | OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE | AOC2, AOC1, AOC3 | HTR3E 4787/4885HTR3B 4608/4885ADRB1 4694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.