Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 12/20 | 0.83 |
| ▸ | DOT1L | Q8TEK3 | 5/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | GALR3 | O60755 | 1/20 | 0.71 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.71 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.64 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.63 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.63 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.63 |
| ▸ | NNMT | P40261 | 1/20 | 0.63 |
| ▸ | DPP4 | P27487 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.62 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20419275 | 1.00 | ADK (0.83) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL20938185 | 1.00 | ADK (0.83) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL2786440 | 1.00 | ADK (0.83) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL2786435 | 1.00 | ADK (0.83) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL20419193 | 1.00 | ADK (0.83) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL20419187 | 1.00 | ADK (0.83) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL30800099 | 1.00 | ADK (0.83) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL8331254 | 0.91 | ADK (1.00) | ADKDOT1LMETTL3PRMT5PRMT3 | |
| SCHEMBL24293493 | 0.90 | ADK (0.67) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL31725326 | 0.90 | ADK (0.71) | ADKDOT1LNPC1GALR3S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210338706-A1 | ADENOSINE ANALOG AND ITS USE IN REGULATING THE CIRCADIAN CLOCK | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-11-04 | — | — | US | disclosed |
| WO-2018133854-A1 | ADENOSINE ANALOG AND ITS USE IN REGULATING THE CIRCADIAN CLOCK | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338706-A1 | ADENOSINE ANALOG AND ITS USE IN REGULATING THE CIRCADIAN CLOCK | PER2, CRY1, ADORA2A | ADK 4/4885DOT1L 1755/4885NPC1 4079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.