Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21556860 | 0.94 | ADRB2 (0.47) | ADRB2ADRA2ADRD2ADRA2CDRD1 | |
| SCHEMBL18459383 | 0.93 | ADRB2 (0.39) | ADRB2ADRA2ADRD2ADRA2CDRD1 | |
| SCHEMBL17754307 | 0.92 | THRB (0.44) | ALOX15THRBKMT2AMAPTAKR1C3 | |
| SCHEMBL20414524 | 0.92 | THRB (0.44) | ALOX15THRBKMT2AMAPTAKR1C3 | |
| SCHEMBL17461532 | 0.88 | THRB (0.47) | ALOX15THRBKMT2AMAPTAKR1C3 | |
| SCHEMBL17461533 | 0.88 | THRB (0.47) | ALOX15THRBKMT2AMAPTAKR1C3 | |
| SCHEMBL19600927 | 0.88 | THRB (0.39) | ADRB2ADRA2ADRD2ADRA2CDRD1 | |
| SCHEMBL17461518 | 0.88 | THRB (0.41) | ADRB2ADRA2ADRD2ADRA2CDRD1 | |
| SCHEMBL19524234 | 0.88 | KMT2A (0.45) | THRBKMT2AMAPTAKR1C3CCR5 | |
| SCHEMBL17754358 | 0.88 | KMT2A (0.41) | ALOX15THRBKMT2AMAPTAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180208846-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE INCLUDING THE SAME | DIC CORPORATION (JP) | 2018-07-26 | — | — | US | disclosed |