Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20420230 | 0.91 | MAPT (0.65) | MAPTSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL20420165 | 0.80 | MAPT (0.58) | MAPTSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL20420265 | 0.79 | KAT2B (0.57) | MAPTSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL22126304 | 0.79 | HCAR3 (0.57) | MAPTLMNAALDH1A1KAT2B | |
| SCHEMBL27653716 | 0.78 | GAA (0.53) | MAPTSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL117687 | 0.78 | GAA (0.56) | MAPTSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL8313808 | 0.78 | MAPT (0.56) | MAPTSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL20420118 | 0.77 | POLB (0.42) | MAPTSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL20419968 | 0.77 | MAPT (0.49) | MAPTSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL20420227 | 0.77 | MAPT (0.51) | MAPTSMN1; SMN2RAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200199174-A1 | NOVEL FLUORESCENT LABELING METHOD | THE UNIVERSITY OF TOKYO (JP) | 2020-06-25 | — | — | US | disclosed |
| US-20200199174-A1 | NOVEL FLUORESCENT LABELING METHOD | THE UNIVERSITY OF TOKYO (JP) | 2020-06-25 | — | — | US | disclosed |
| WO-2018135598-A1 | NOVEL FLUORESCENT LABELING METHOD | 国立大学法人 東京大学 | 2018-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200199174-A1 | NOVEL FLUORESCENT LABELING METHOD | RPS27A, DNPEP, DNM1L | MAPT 1510/4885SMN1; SMN2 3697/4885RAB9A 674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.