Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20420230 | 0.80 | MAPT (0.65) | POLBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL20420121 | 0.77 | MAPT (0.53) | POLBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9363364 | 0.72 | ALDH1A1 (0.43) | POLBMAPTSMN1; SMN2PDE3BPDE3A | |
| SCHEMBL30600294 | 0.70 | ALDH1A1 (0.39) | POLBMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3451748 | 0.68 | RXRA (0.50) | MAPTLMNAIDO1HTTCES2 | |
| SCHEMBL9363550 | 0.68 | POLB (0.49) | POLBMAPTPDE3BPDE3AALDH1A1 | |
| SCHEMBL25039465 | 0.67 | CA1 (0.44) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL8342305 | 0.67 | PTGER4 (0.56) | MAPTSMN1; SMN2NPC1RAB9APDE3B | |
| SCHEMBL9362895 | 0.67 | PDE3B (0.49) | POLBMAPTPDE3BPDE3AALDH1A1 | |
| Bromide SCHEMBL20984179 | 0.67 | ALDH1A1 (0.52) | POLBMAPTRAB9AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200199174-A1 | NOVEL FLUORESCENT LABELING METHOD | THE UNIVERSITY OF TOKYO (JP) | 2020-06-25 | — | — | US | disclosed |
| WO-2018135598-A1 | NOVEL FLUORESCENT LABELING METHOD | 国立大学法人 東京大学 | 2018-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200199174-A1 | NOVEL FLUORESCENT LABELING METHOD | RPS27A, DNPEP, DNM1L | POLB 4387/4885MAPT 1510/4885SMN1; SMN2 3697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.