Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN9 | O14815 | 3/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 11/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSH | P09668 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | CTSC | P53634 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | NPY4R | P50391 | 4/20 | 0.38 |
| ▸ | NPY1R | P25929 | 3/20 | 0.38 |
| ▸ | NPY2R | P49146 | 3/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23133278 | 1.00 | CAPN9 (0.53) | CAPN9CAPN1CTSKCTSBMAPK1 | |
| SCHEMBL20422767 | 1.00 | CAPN9 (0.53) | CAPN9CAPN1CTSKCTSBMAPK1 | |
| SCHEMBL20422771 | 1.00 | CAPN9 (0.53) | CAPN9CAPN1CTSKCTSBMAPK1 | |
| SCHEMBL22687573 | 1.00 | CAPN9 (0.53) | CAPN9CAPN1CTSKCTSBMAPK1 | |
| SCHEMBL22687572 | 1.00 | CAPN9 (0.53) | CAPN9CAPN1CTSKCTSBMAPK1 | |
| E-64 SCHEMBL13283063 | 0.81 | CAPN1 (0.74) | CAPN9CAPN1CTSKCTSBMAPK1 | |
| E-64 SCHEMBL23132676 | 0.81 | CAPN1 (0.74) | CAPN9CAPN1CTSKCTSBMAPK1 | |
| E-64 SCHEMBL13523481 | 0.81 | CAPN1 (0.74) | CAPN9CAPN1CTSKCTSBMAPK1 | |
| E-64 SCHEMBL16452857 | 0.81 | CAPN1 (0.74) | CAPN9CAPN1CTSKCTSBMAPK1 | |
| E-64 SCHEMBL7087294 | 0.81 | CAPN1 (0.74) | CAPN9CAPN1CTSKCTSBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11000535-B2 | Anticancer composition and use thereof | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2021-05-11 | — | — | US | disclosed |
| US-20180214469-A1 | ANTICANCER COMPOSITION AND USE THEREOF | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2018-08-02 | — | — | US | disclosed |