Luteolin

Luteolin

SCHEMBL20426

O=c1cc(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLH Q9Y253 8/20 1.00
MEN1 O00255 6/20 1.00
MAPT P10636 6/20 1.00
KMT2A Q03164 6/20 1.00
CYP1B1 Q16678 6/20 1.00
ALDH1A1 P00352 5/20 1.00
ABCB1 P08183 5/20 1.00
KDM4E B2RXH2 5/20 1.00
CYP3A4 P08684 5/20 1.00
HSD17B10 Q99714 5/20 1.00
CYP1A1 P04798 5/20 1.00
CYP1A2 P05177 5/20 1.00
HPGD P15428 4/20 1.00
ALOX15 P16050 4/20 1.00
FTO Q9C0B1 4/20 1.00
XDH P47989 4/20 1.00
HDAC6 Q9UBN7 4/20 1.00
IP6K2 Q9UHH9 4/20 1.00
CYP2C9 P11712 4/20 1.00
CYP2C19 P33261 4/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Luteolin SCHEMBL28256564 1.00 POLH (1.00) POLHMEN1MAPTKMT2ACYP1B1
Luteolin SCHEMBL30045580 1.00 POLH (1.00) POLHMEN1MAPTKMT2ACYP1B1
Luteolin SCHEMBL29352380 1.00 POLH (1.00) POLHMEN1MAPTKMT2ACYP1B1
Luteolin SCHEMBL29376494 1.00 POLH (1.00) POLHMEN1MAPTKMT2ACYP1B1
Luteolin SCHEMBL31168048 0.98 POLH (0.97) POLHMEN1MAPTKMT2ACYP1B1
Luteolin SCHEMBL31678931 0.98 POLH (0.97) POLHMEN1MAPTKMT2ACYP1B1
Luteolin SCHEMBL1659262 0.98 POLH (0.97) POLHMEN1MAPTKMT2ACYP1B1
Luteolin SCHEMBL31542150 0.98 POLH (0.97) POLHMEN1MAPTKMT2ACYP1B1
Luteolin SCHEMBL31539190 0.98 POLH (0.97) POLHMEN1MAPTKMT2ACYP1B1
Luteolin SCHEMBL31258014 0.98 POLH (0.97) POLHMEN1MAPTKMT2ACYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 29132 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12636311-B2 Topically administered strontium-containing complexes for treating pain, pruritis and inflammation GALLEON LABS LLC (US) 2026-05-26 US claimed
CN-122080093-A Compounds effective in treating liver toxicity and fatty liver disease and uses thereof 2026-05-26 CN claimed
CN-122075560-A Application of total flavonoids of sea buckthorn leaves in preparing medicines for treating ulcerative colitis 2026-05-26 CN claimed
CN-122080098-A S-adenosyl homocysteine analogue, S-adenosyl-L-methionine analogue and application thereof 2026-05-26 CN claimed
CN-122084727-A Method for detecting and separating eight flavonoid glycoside compounds with similar structures by utilizing capillary zone electrophoresis 2026-05-26 CN claimed
CN-122075474-A Application of gamboge C 2026-05-26 CN claimed
CN-121378801-B Photo-crosslinking double-network hydrogel for promoting skin wound healing and preparation method thereof Shandong second people's Hospital (Shandong ear nose throat hospital, Shandong ear nose throat Research Institute) (CN) 2026-05-26 CN claimed
WO-2026106917-A1 EDIBLE TRANSMUCOSAL DRUG DELIVERY METHOD USING AN INTERMEDIATE CAPSULE AS A TEMPORARY VESSEL BioPhysics Pharma, Inc. (US) 2026-05-21 WO claimed
WO-2026107510-A1 HOT-MELT ADHESIVE COMPOSITION AND METHOD OF APPLICATION BIOBOND ADHESIVES, INC. (US) 2026-05-21 WO claimed
CN-122063228-A Quality control method for reference sample of five-flavor disinfection drink 江苏海洋大学 2026-05-19 CN claimed
EP-0496349-A1 Coating solution for preventing adhesion of polymer scale and method for its use SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-07-29 EP claimed
US-5043323-A Complex compounds of bioflavonoids with phospholipids, their preparation and use, and pharmaceutical and cosmetic compositions containing them INDENA S.P.A. (IT) 1991-08-27 US claimed
EP-0290442-A4 PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS. CHEMEX PHARMACEUTICALS INC (US) 1990-07-03 EP claimed
US-4885244-A CONTACTING MICROORGANISM WITH SACCHARIDE IN POLYHYDRIC AROMATIC COMPOUND CONTAINING MEDIUM; HIGH MOLECULAR WEIGHT MITSUBISHI RAYON CO., LTD. (JP) 1989-12-05 US claimed
EP-0206219-B1 PHOTOSTABILISING OF SYDNONIMINES CASSELLA Aktiengesellschaft (DE) 1989-09-06 EP claimed
EP-0290442-A1 PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS CHEMEX PHARMACEUTICALS, INC. (US) 1988-11-17 EP claimed
EP-0275005-A2 Complex compounds of bioflavonoids with phospholipids, their preparation and use, and pharmaceutical and cosmetic compositions containing them INDENA S.p.A. (IT) 1988-07-20 EP claimed
WO-1988003805-A1 PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS CHEMEX PHARMACEUTICALS, INC. (US) 1988-06-02 WO claimed
EP-0206219-A1 Photostabilising of sydnonimines CASSELLA Aktiengesellschaft (DE) 1986-12-30 EP claimed
US-4617293-A Flavonoid phosphate salts of aminoglycoside antibiotics MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1986-10-14 US claimed