Luteolin

Luteolin

SCHEMBL29376494

O=c1cc(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLH Q9Y253 8/20 1.00
MEN1 O00255 6/20 1.00
MAPT P10636 6/20 1.00
KMT2A Q03164 6/20 1.00
CYP1B1 Q16678 6/20 1.00
ALDH1A1 P00352 5/20 1.00
ABCB1 P08183 5/20 1.00
KDM4E B2RXH2 5/20 1.00
CYP3A4 P08684 5/20 1.00
HSD17B10 Q99714 5/20 1.00
CYP1A1 P04798 5/20 1.00
CYP1A2 P05177 5/20 1.00
HPGD P15428 4/20 1.00
ALOX15 P16050 4/20 1.00
FTO Q9C0B1 4/20 1.00
XDH P47989 4/20 1.00
HDAC6 Q9UBN7 4/20 1.00
IP6K2 Q9UHH9 4/20 1.00
CYP2C9 P11712 4/20 1.00
CYP2C19 P33261 4/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Luteolin SCHEMBL20426 1.00 POLH (1.00) POLHMEN1MAPTKMT2ACYP1B1
Luteolin SCHEMBL28256564 1.00 POLH (1.00) POLHMEN1MAPTKMT2ACYP1B1
Luteolin SCHEMBL30045580 1.00 POLH (1.00) POLHMEN1MAPTKMT2ACYP1B1
Luteolin SCHEMBL29352380 1.00 POLH (1.00) POLHMEN1MAPTKMT2ACYP1B1
Luteolin SCHEMBL31168048 0.98 POLH (0.97) POLHMEN1MAPTKMT2ACYP1B1
Luteolin SCHEMBL31678931 0.98 POLH (0.97) POLHMEN1MAPTKMT2ACYP1B1
Luteolin SCHEMBL1659262 0.98 POLH (0.97) POLHMEN1MAPTKMT2ACYP1B1
Luteolin SCHEMBL31542150 0.98 POLH (0.97) POLHMEN1MAPTKMT2ACYP1B1
Luteolin SCHEMBL31539190 0.98 POLH (0.97) POLHMEN1MAPTKMT2ACYP1B1
Luteolin SCHEMBL31258014 0.98 POLH (0.97) POLHMEN1MAPTKMT2ACYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719404-A2 METHODS FOR ADDRESSING INJECTION SITE REACTIONS ASSOCIATED WITH THE ADMINISTRATION OF BEVEMIPRETIDE Stealth BioTherapeutics Inc. (US) 2026-04-08 EP claimed
WO-2025229086-A1 ADHESIVE COSMETIC COMPOUNDS AND USES THEREOF SKINOSIVE (FR) 2025-11-06 WO claimed
CN-119453207-A Submicron antibacterial material, preparation method of medical material doped with submicron antibacterial material and antibacterial catheter 广东广纳特飞科技有限公司 2025-02-18 CN claimed
CN-119080728-A Preparation method of 3',4',5, 7-tetrahydroxyflavone and derivative plant extract thereof and uric acid reducing application 山东大学 2024-12-06 CN claimed
WO-2024243490-A2 METHODS FOR ADDRESSING INJECTION SITE REACTIONS ASSOCIATED WITH THE ADMINISTRATION OF BEVEMIPRETIDE STEALTH BIOTHERAPEUTICS INC. (US) 2024-11-28 WO claimed
CN-117547613-A Preparation method and application of luteolin-loaded glucose-ferritin compound 南京林业大学 2024-02-13 CN claimed
CN-116236449-A Polyvinyl alcohol luteolin-Fe-loaded microsphere and preparation method and application thereof 复旦大学附属肿瘤医院 2023-06-09 CN claimed
CN-115282142-A Application of luteolin in preparation of medicine for treating gastric precancerous diseases 北京大学第三医院(北京大学第三临床医学院) 2022-11-04 CN claimed
US-20220257500-A1 USE OF A HYDRO-ALCOHOLIC EXTRACT OF EVENING PRIMROSE FOR HYDRATING SKIN AND INCREASING BARRIER FUNCTION L'OREAL (FR) 2022-08-18 US claimed
CN-114796188-A Plant-derived flavone antibacterial compound and application thereof 朱奎 2022-07-29 CN claimed
CN-114642677-A Stable liquid medicine composition containing ilexoside compound 上海凯屹医药科技有限公司 2022-06-21 CN claimed
EP-4003522-A1 ANTIMYCOTIC Karl-Franzens-Universität Graz (AT) 2022-06-01 EP claimed
EP-3989928-A1 USE OF A HYDRO-ALCOHOLIC EXTRACT OF EVENING PRIMROSE FOR HYDRATING SKIN AND INCREASING BARRIER FUNCTION L'OREAL (FR) 2022-05-04 EP claimed
CN-120330281-B Highland barley flavonoid compound glycosyltransferase gene and application thereof INSTITUTE OF AGRICULTURE, TIBET AUTONOMOUS REGION ACADEMY OF AGRICULTURE AND ANIMAL HUSBANDRY (CN) 2026-05-26 CN disclosed
EP-4728879-A1 MEMORY DISORDER AMELIORATING AGENT National University Corporation Kobe University (JP) 2026-04-22 EP disclosed
CN-121533460-A Preparation method and application of plant extract fermentation product for promoting dog anti-aging 卫仕宠物营养研究院(芜湖)有限公司 2026-02-17 CN disclosed
CN-114146140-A Medicine formula for treating leukemia 陈涵 2022-03-08 CN disclosed
CN-114099685-A Application of substance for inhibiting MUC1 expression and glycosylation modification in reducing drug resistance of anti-breast cancer drugs 中国农业大学 2022-03-01 CN disclosed
US-20220054425-A1 NANOCAPSULES COATED WITH CHITOSAN AND USE THEREOF SKINMED CO., LTD. (KR) 2022-02-24 US disclosed
US-20220047650-A1 MICROBIAL COMPOSITIONS TO INCREASE THE PRODUCTION OF PCA FROM POLYPHENOLS CHURCH & DWIGHT CO., INC. (US) 2022-02-17 US disclosed