Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4481165 | 0.87 | KDM4E (0.38) | TAAR1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL20428033 | 0.87 | TAAR1 (0.40) | TAAR1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6984300 | 0.83 | TAAR1 (0.55) | TAAR1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27635788 | 0.77 | TAAR1 (0.57) | TAAR1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL805461 | 0.77 | TAAR1 (0.61) | TAAR1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13228082 | 0.73 | TAAR1 (0.68) | TAAR1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL12561924 | 0.73 | TAAR1 (0.61) | TAAR1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL20427978 | 0.72 | KDM4E (0.36) | TAAR1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8341494 | 0.71 | TAAR1 (0.50) | TAAR1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19954215 | 0.71 | HTT (0.53) | TAAR1GAAKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10035790-B2 | RORγ modulators | EXELIXIS, INC. (US) | 2018-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10035790-B2 | RORγ modulators | RORB, RORA, RORC | TAAR1 1070/4885GAA 2832/4885KMT2A 2258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.