Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 5-Fluorodeoxyuridylate SCHEMBL973436 | 0.90 | LMNA (0.71) | TYMSLMNASMN1; SMN2 | |
| 5-Fluorodeoxyuridylate SCHEMBL6107 | 0.90 | LMNA (0.71) | TYMSLMNASMN1; SMN2 | |
| 5-Fluorodeoxyuridylate SCHEMBL21901970 | 0.90 | LMNA (0.71) | TYMSLMNASMN1; SMN2 | |
| 5-Fluorodeoxyuridylate SCHEMBL15189164 | 0.90 | LMNA (0.71) | TYMSLMNASMN1; SMN2 | |
| 5-Fluorodeoxyuridylate SCHEMBL17117772 | 0.90 | LMNA (0.71) | TYMSLMNASMN1; SMN2 | |
| SCHEMBL5491971 | 0.89 | LMNA (0.67) | TYMSLMNASMN1; SMN2 | |
| SCHEMBL13026822 | 0.87 | LMNA (0.67) | TYMSLMNASMN1; SMN2 | |
| SCHEMBL28378385 | 0.86 | LMNA (0.66) | TYMSLMNASMN1; SMN2 | |
| 5-Fluorodeoxyuridylate SCHEMBL25223991 | 0.86 | LMNA (0.69) | TYMSLMNASMN1; SMN2 | |
| SCHEMBL5491976 | 0.86 | LMNA (0.69) | TYMSLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3031812-B1 | CHEMICAL COMPOUNDS | NuCana plc (GB) | 2018-08-01 | — | — | EP | disclosed |