5-Fluorodeoxyuridylate

5-Fluorodeoxyuridylate

SCHEMBL973436

O=c1[nH]c(=O)n([C@@H]2CC(O)[C@H](COP(=O)(O)O)O2)cc1F

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
TYMS P04818 5/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
5-Fluorodeoxyuridylate SCHEMBL6107 1.00 LMNA (0.71) LMNASMN1; SMN2TYMS
5-Fluorodeoxyuridylate SCHEMBL17117772 1.00 LMNA (0.71) LMNASMN1; SMN2TYMS
5-Fluorodeoxyuridylate SCHEMBL21901970 1.00 LMNA (0.71) LMNASMN1; SMN2TYMS
5-Fluorodeoxyuridylate SCHEMBL15189164 1.00 LMNA (0.71) LMNASMN1; SMN2TYMS
SCHEMBL5491971 0.93 LMNA (0.67) LMNASMN1; SMN2TYMS
SCHEMBL13026822 0.93 LMNA (0.67) LMNASMN1; SMN2TYMS
5-Fluorodeoxyuridylate SCHEMBL15671694 0.92 TYMS (0.64) LMNASMN1; SMN2TYMS
SCHEMBL28378385 0.92 LMNA (0.66) LMNASMN1; SMN2TYMS
5-Fluorodeoxyuridylate SCHEMBL25223991 0.91 LMNA (0.69) LMNASMN1; SMN2TYMS
SCHEMBL5491976 0.91 LMNA (0.69) LMNASMN1; SMN2TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2935331-B1 PROLACTIN RECEPTOR BINDING PROTEINS AND USES THEREOF ABBVIE INC (US) 2018-02-28 EP claimed
US-20140227294-A1 PROLACTIN RECEPTOR BINDING PROTEINS AND USES THEREOF ABBVIE INC. (US) 2014-08-14 US claimed
WO-2026090505-A1 FLUOROPYRIMIDINE PARTICLES FOR THE TREATMENT OF CANCER WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2026-04-30 WO disclosed
US-12551570-B2 Compounds comprising cleavable linker and uses thereof INTOCELL, INC. (KR) 2026-02-17 US disclosed
US-12479927-B2 Compounds comprising cleavable linker and uses thereof INTOCELL, INC. (KR) 2025-11-25 US disclosed
US-20250186435-A1 PHARMACEUTICAL FORMULATIONS AND THEIR PREPARATIONS FOR TREATMENT OF CANCER CELLIX BIO PRIVATE LIMITED (IN) 2025-06-12 US disclosed
US-20250163159-A1 ANTI-EGFR ANTIBODIES AND ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2025-05-22 US disclosed
US-20250121087-A1 ANTIBODY-DRUG CONJUGATES COMPRISING ANTI-B7-H3 ANTIBODIES INTOCELL, INC. (KR) 2025-04-17 US disclosed
US-12168060-B2 Antibody-drug conjugates comprising anti-B7-H3 antibodies INTOCELL, INC. (KR) 2024-12-17 US disclosed
EP-4364754-A2 ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES AbbVie Inc. (US) 2024-05-08 EP disclosed
US-20230406877-A1 COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF INTOCELL, INC. (KR) 2023-12-21 US disclosed
WO-1998026786-A1 CAGED MEMBRANE-PERMEANT INOSITOL PHOSPHATES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-06-25 WO disclosed
US-5760022-A ESTER, ETHER PERSTORP AB (SE) 1998-06-02 US disclosed
EP-0842181-A1 MEMBRANE-PERMEANT SECOND MESSENGERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-05-20 EP disclosed
US-5693521-A USING ACETOXYALKYL ESTER OF ADENOSINE(OR GUANOSINE)-3',5'-CYCLIC MONNOPHOSPHATE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1997-12-02 US disclosed
US-5614510-A AMMONIUM SALTS PERSTORP AB (SE) 1997-03-25 US disclosed
WO-1996040695-A1 MEMBRANE-PERMEANT SECOND MESSENGERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1996-12-19 WO disclosed
EP-0627922-A1 A PHARMACEUTICAL COMPOSITION WITH IMPROVED BIOAVAILABILITY OF INOSITOL PHOSPHATE PERSTORP AB (SE) 1994-12-14 EP disclosed
WO-1994023724-A1 MEMBRANE-PERMEANT SECOND MESSENGERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1994-10-27 WO disclosed
WO-1993016705-A1 A PHARMACEUTICAL COMPOSITION WITH IMPROVED BIOAVAILABILITY OF INOSITOL PHOSPHATE PERSTORP AB (SE) 1993-09-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140227294-A1 PROLACTIN RECEPTOR BINDING PROTEINS AND USES THEREOF PRLHR, LHCGR, FCGR2A LMNA 4140/4885SMN1; SMN2 4100/4885TYMS 4342/4885
US-20250121087-A1 ANTIBODY-DRUG CONJUGATES COMPRISING ANTI-B7-H3 ANTIBODIES CD274, CD44, H1-3 LMNA 3972/4885SMN1; SMN2 3166/4885TYMS 2954/4885
US-12551570-B2 Compounds comprising cleavable linker and uses thereof FCGR2A, FCGR3B, FCGR1A LMNA 456/4885SMN1; SMN2 3041/4885TYMS 2903/4885
US-20230406877-A1 COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF VIP, ANTXR2, TNFRSF9 LMNA 3724/4885SMN1; SMN2 2658/4885TYMS 1060/4885
US-12168060-B2 Antibody-drug conjugates comprising anti-B7-H3 antibodies CD274, CD44, H1-3 LMNA 3972/4885SMN1; SMN2 3166/4885TYMS 2954/4885
US-12479927-B2 Compounds comprising cleavable linker and uses thereof VIP, ANTXR2, TNFRSF9 LMNA 3724/4885SMN1; SMN2 2658/4885TYMS 1060/4885
US-20250163159-A1 ANTI-EGFR ANTIBODIES AND ANTIBODY DRUG CONJUGATES EGFR, ERBB2, ERBB3 LMNA 4745/4885SMN1; SMN2 4687/4885TYMS 1744/4885
US-20250186435-A1 PHARMACEUTICAL FORMULATIONS AND THEIR PREPARATIONS FOR TREATMENT OF CANCER SLC5A1, DPYD, SLC46A1 LMNA 4234/4885SMN1; SMN2 1316/4885TYMS 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.