Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 6/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20428404 | 0.90 | MEN1 (0.49) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL20420749 | 0.83 | L3MBTL1 (0.47) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL20428400 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL20420735 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL20420770 | 0.82 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL31005008 | 0.81 | NQO1 (0.49) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL20420753 | 0.81 | CA12 (0.48) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL20420720 | 0.81 | NQO1 (0.49) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL20428284 | 0.81 | ACHE (0.45) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL20420797 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3354648-A1 | 4-SUBSTITUED COUMARIN DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | Guizhou Bailing Group Pharmaceutical Co., Ltd. (CN) | 2018-08-01 | — | — | EP | disclosed |