Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.55 |
| ▸ | PPARG | P37231 | 7/20 | 0.55 |
| ▸ | PPARD | Q03181 | 7/20 | 0.55 |
| ▸ | PPARA | Q07869 | 7/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | FABP4 | P15090 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TLR2 | O60603 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1986747 | 1.00 | KMT2A (0.60) | KMT2AMAPTGPR84PPARGPPARD | |
| SCHEMBL4350830 | 0.98 | KMT2A (0.62) | KMT2AMAPTGPR84PPARGPPARD | |
| SCHEMBL20875703 | 0.98 | KMT2A (0.62) | KMT2AMAPTGPR84PPARGPPARD | |
| SCHEMBL22325563 | 0.89 | KMT2A (0.64) | KMT2AMAPTGPR84PPARGPPARD | |
| SCHEMBL27836698 | 0.89 | KMT2A (0.64) | KMT2AMAPTGPR84PPARGPPARD | |
| SCHEMBL22325566 | 0.87 | KMT2A (0.67) | KMT2AMAPTGPR84PPARGPPARD | |
| SCHEMBL9744779 | 0.87 | KMT2A (0.67) | KMT2AMAPTGPR84PPARGPPARD | |
| SCHEMBL15286057 | 0.87 | KMT2A (0.67) | KMT2AMAPTGPR84PPARGPPARD | |
| SCHEMBL22591965 | 0.85 | KMT2A (0.52) | KMT2AMAPTGPR84PPARGPPARD | |
| SCHEMBL571788 | 0.84 | GPR84 (0.52) | KMT2AMAPTGPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023053677-A1 | LIQUID SKIN EXTERNAL COMPOSITION | ライオン株式会社 | 2023-04-06 | — | — | WO | disclosed |
| WO-2023276272-A1 | LIQUID SKIN CLEANSER COMPOSITION | ライオン株式会社 | 2023-01-05 | — | — | WO | disclosed |
| WO-2022270014-A1 | SKIN CLEANING AGENT COMPOSITION | ライオン株式会社 | 2022-12-29 | — | — | WO | disclosed |
| WO-2022264507-A1 | LIQUID SKIN CLEANSER COMPOSITION | ライオン株式会社 | 2022-12-22 | — | — | WO | disclosed |
| WO-2020166190-A1 | HAIR DETERGENT COMPOSITION | ライオン株式会社 | 2020-08-20 | — | — | WO | disclosed |
| EP-1381651-B1 | POLYORGANOSILOXANE EMULSION COMPOSITION AND A COSMETIC MATERIAL MADE THEREFROM | DOW CORNING TORAY CO LTD (JP) | 2011-06-29 | — | — | EP | disclosed |
| EP-1858982-B1 | SILICONE EMULSION, METHOD OF PREPARING SAME, AND COSMETIC INGREDIENT | DOW CORNING (US) | 2008-08-27 | — | — | EP | disclosed |
| US-20080182833-A1 | Silicone Emulsion, Method of Preparing Same, and Cosmetic Ingredient | DOW CORNING CORPORATION | 2008-07-31 | — | — | US | disclosed |
| EP-1858982-A1 | SILICONE EMULSION, METHOD OF PREPARING SAME, AND COSMETIC INGREDIENT | Dow Corning Corporation (US) | 2007-11-28 | — | — | EP | disclosed |
| US-7300648-B2 | Polyorganosiloxane emulsion composition and a cosmetic material made therefrom | DOWECORNING TORAY SILICONE, CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |
| WO-2006102010-A1 | SILICONE EMULSION, METHOD OF PREPARING SAME, AND COSMETIC INGREDIENT | DOW CORNING CORPORATION (US) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182833-A1 | Silicone Emulsion, Method of Preparing Same, and Cosmetic Ingredient | SQLE, CUTA, SMOX | KMT2A 2689/4885MAPT 3009/4885GPR84 541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.