Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 18/20 | 0.46 |
| ▸ | TPO | P07202 | 1/20 | 0.46 |
| ▸ | EPX | P11678 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19282239 | 0.88 | MPO (0.47) | MPOTPOEPX | |
| SCHEMBL19282248 | 0.86 | MPO (0.61) | MPOTPOEPXMETAP2 | |
| SCHEMBL19294232 | 0.84 | MPO (0.56) | MPOTPOEPXMETAP2 | |
| SCHEMBL19282191 | 0.84 | MPO (0.67) | MPOTPOEPX | |
| SCHEMBL20429877 | 0.84 | MPO (0.51) | MPOTPOEPX | |
| SCHEMBL19282355 | 0.84 | MPO (0.66) | MPOTPOEPX | |
| SCHEMBL20420866 | 0.83 | MPO (0.55) | MPOTPOEPXMETAP2 | |
| SCHEMBL19282344 | 0.82 | MPO (0.70) | MPOTPOEPXMETAP2 | |
| SCHEMBL19294222 | 0.82 | RAB9A (0.52) | MPO | |
| SCHEMBL20429882 | 0.82 | SMN1; SMN2 (0.46) | MPOTPOEPXMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191486-B1 | THIOETHER TRIAZOLOPYRIDINE AND TRIAZOLOPYRMIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL MYERS SQUIBB CO (US) | 2018-08-01 | — | — | EP | disclosed |