Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 3/20 | 0.34 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.34 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21499685 | 0.93 | TRPC5 (0.43) | TRPC5TRPC1TRPC4CTSA | |
| SCHEMBL19505557 | 0.91 | P2RX3 (0.34) | P2RX3 | |
| SCHEMBL21499681 | 0.90 | P2RX3 (0.40) | TRPC5TRPC4P2RX3 | |
| SCHEMBL20432298 | 0.85 | TRPC5 (0.33) | TRPC5TRPC1TRPC4P2RX3 | |
| SCHEMBL20432382 | 0.84 | TRPC5 (0.40) | TRPC5TRPC1TRPC4HCRTR1HCRTR2 | |
| SCHEMBL19375459 | 0.84 | TRPC5 (0.43) | TRPC5TRPC1TRPC4P2RX3 | |
| SCHEMBL21499664 | 0.79 | TRPC5 (0.44) | TRPC5TRPC1TRPC4CTSA | |
| SCHEMBL19375432 | 0.79 | TRPC5 (0.43) | TRPC5TRPC1TRPC4 | |
| SCHEMBL19505559 | 0.77 | PDE5A (0.31) | — | |
| SCHEMBL21499677 | 0.77 | TRPC5 (0.51) | TRPC5TRPC1TRPC4HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B3 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2018-08-01 | — | — | EP | disclosed |