Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 15/20 | 0.46 |
| ▸ | PDE5A | O76074 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21499718 | 0.90 | P2RX3 (0.47) | P2RX3 | |
| SCHEMBL21499684 | 0.87 | P2RX3 (0.44) | P2RX3PDE5A | |
| SCHEMBL19375680 | 0.83 | TRPC4 (0.46) | P2RX3PDE5A | |
| SCHEMBL20432416 | 0.83 | P2RX3 (0.39) | P2RX3PDE5A | |
| SCHEMBL19375611 | 0.82 | TRPC4 (0.41) | P2RX3PDE5A | |
| SCHEMBL18834422 | 0.82 | P2RX3 (0.47) | P2RX3 | |
| SCHEMBL19505233 | 0.80 | P2RX3 (0.45) | P2RX3PDE5A | |
| SCHEMBL20432442 | 0.80 | TRPC5 (0.48) | P2RX3 | |
| SCHEMBL19505396 | 0.80 | TRPC4 (0.41) | P2RX3PDE5A | |
| SCHEMBL19505394 | 0.80 | TRPC5 (0.48) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B3 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2018-08-01 | — | — | EP | disclosed |