Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GUCY1B2 | O75343 | 2/20 | 0.38 |
| ▸ | GUCY1A2 | P33402 | 2/20 | 0.38 |
| ▸ | GUCY1A1 | Q02108 | 2/20 | 0.38 |
| ▸ | GUCY1B1 | Q02153 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24131052 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL17611691 | 0.77 | P2RY14 (0.57) | ALDH1A1MEN1KMT2APKML3MBTL1 | |
| SCHEMBL20433971 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14998053 | 0.73 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL18672320 | 0.73 | P2RY14 (0.45) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL255982 | 0.72 | CYP1A2 (0.44) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL175092 | 0.71 | TP53 (0.47) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL30223258 | 0.71 | TP53 (0.47) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL6859115 | 0.71 | ADORA2A (0.52) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL6859181 | 0.71 | PDE5A (0.42) | ALDH1A1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782914-B1 | METHOD FOR PRODUCING SUBSTITUTED 5-FLUORO-1H-PYRAZOLOPYRIDINES | ADVERIO PHARMA GMBH (DE) | 2018-08-01 | — | — | EP | disclosed |