Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.38 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.38 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18672320 | 0.88 | P2RY14 (0.45) | ALDH1A1CYP1A2CYP2C19P2RY14CYP2C9 | |
| SCHEMBL14998053 | 0.88 | ALDH1A1 (0.55) | ALDH1A1CYP1A2CYP2C19P2RY14CYP2C9 | |
| SCHEMBL30223258 | 0.85 | TP53 (0.47) | ALDH1A1CYP1A2CYP2C19P2RY14CYP2C9 | |
| SCHEMBL175092 | 0.85 | TP53 (0.47) | ALDH1A1CYP1A2CYP2C19P2RY14CYP2C9 | |
| SCHEMBL17611691 | 0.84 | P2RY14 (0.57) | ALDH1A1CYP1A2CYP2C19P2RY14KMT2A | |
| SCHEMBL18496413 | 0.82 | TP53 (0.45) | ALDH1A1CYP1A2CYP2C19P2RY14CYP2C9 | |
| SCHEMBL255982 | 0.79 | CYP1A2 (0.44) | ALDH1A1CYP1A2CYP2C19P2RY14CYP2C9 | |
| SCHEMBL6068367 | 0.76 | TP53 (0.43) | ALDH1A1CYP1A2P2RY14KMT2AMEN1 | |
| SCHEMBL20433786 | 0.73 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2C19P2RY14KMT2A | |
| SCHEMBL29831851 | 0.72 | CYP1A2 (0.54) | ALDH1A1CYP1A2CYP2C19P2RY14CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782914-B1 | METHOD FOR PRODUCING SUBSTITUTED 5-FLUORO-1H-PYRAZOLOPYRIDINES | ADVERIO PHARMA GMBH (DE) | 2018-08-01 | — | — | EP | disclosed |