Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18506356 | 0.93 | KDM4E (0.56) | KDM4EADRB3KMT2AALDH1A1MEN1 | |
| SCHEMBL20436123 | 0.89 | ADRB3 (0.54) | ADRB3KMT2AMEN1OPRM1OPRD1 | |
| SCHEMBL10738074 | 0.86 | ADRB2 (0.65) | KDM4EADRB3KMT2AALDH1A1MEN1 | |
| SCHEMBL10770040 | 0.84 | ADRB3 (0.51) | KDM4EADRB3KMT2AALDH1A1MEN1 | |
| SCHEMBL7327969 | 0.83 | MEN1 (0.68) | ADRB3KMT2AMEN1OPRM1OPRD1 | |
| SCHEMBL11922778 | 0.83 | MEN1 (0.68) | ADRB3KMT2AALDH1A1MEN1OPRM1 | |
| SCHEMBL20436115 | 0.83 | ADRB3 (0.54) | ADRB3KMT2AMEN1ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL10345932 | 0.81 | MEN1 (0.67) | ADRB3KMT2AMEN1OPRM1OPRD1 | |
| SCHEMBL18506359 | 0.81 | ADRB3 (0.60) | ADRB3KMT2AMEN1OPRM1OPRD1 | |
| SCHEMBL10836940 | 0.81 | ATM (0.53) | ADRB3KMT2AALDH1A1MEN1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180215863-A1 | AMINE FOR LOW-EMISSION EPOXY RESIN COMPOSITIONS | SIKA TECHNOLOGY AG (CH) | 2018-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180215863-A1 | AMINE FOR LOW-EMISSION EPOXY RESIN COMPOSITIONS | EEF1A1, EEF1A2, EEF1E1 | KDM4E 54/4885ADRB3 1748/4885KMT2A 507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.