Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | GMNN | O75496 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2602822 | 0.86 | FABP3 (0.48) | RECQLPLA2G10MAPK1LMNAMAPT | |
| SCHEMBL21631754 | 0.84 | LMNA (0.67) | RECQLSMN1; SMN2PLA2G10LMNAMAPT | |
| SCHEMBL2837952 | 0.82 | RECQL (0.57) | RECQLSMN1; SMN2PLA2G10MAPK1LMNA | |
| SCHEMBL2232537 | 0.81 | RECQL (0.66) | RECQLSMN1; SMN2MAPK1LMNAMAPT | |
| SCHEMBL2234409 | 0.81 | RECQL (0.66) | RECQLSMN1; SMN2MAPK1LMNAMAPT | |
| SCHEMBL704034 | 0.81 | RECQL (0.81) | RECQLSMN1; SMN2MAPK1LMNAMAPT | |
| SCHEMBL2232633 | 0.81 | RECQL (0.81) | RECQLSMN1; SMN2MAPK1LMNAMAPT | |
| Vb-201 SCHEMBL2071110 | 0.81 | RECQL (0.81) | RECQLSMN1; SMN2MAPK1LMNAMAPT | |
| SCHEMBL2232585 | 0.81 | RECQL (0.81) | RECQLSMN1; SMN2MAPK1LMNAMAPT | |
| Vb-201 SCHEMBL14322398 | 0.81 | RECQL (0.81) | RECQLSMN1; SMN2MAPK1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180214543-A1 | Motile Sperm Domain Containing Protein 2 and Inflammation | IMMUNEWALK THERAPEUTICS, INC. | 2018-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180214543-A1 | Motile Sperm Domain Containing Protein 2 and Inflammation | NASP, CATSPER1, SPAG5 | RECQL 1131/4885SMN1; SMN2 1548/4885PLA2G10 561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.