Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.37 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937699 | 0.82 | ALDH1A1 (0.40) | MAP3K5ALDH1A1GAAHPGDPOLB | |
| Hydrochloric Acid SCHEMBL7473828 | 0.80 | ALDH1A1 (0.39) | MAP3K5ALDH1A1GAAHPGDPOLB | |
| SCHEMBL17114031 | 0.80 | ALDH1A1 (0.45) | MAP3K5ALDH1A1GAAHPGDPOLB | |
| SCHEMBL512864 | 0.76 | ALDH1A1 (0.68) | ALDH1A1GAAHPGDPOLBTP53 | |
| SCHEMBL32691229 | 0.76 | ALDH1A1 (0.68) | ALDH1A1GAAHPGDPOLBTP53 | |
| SCHEMBL20835844 | 0.76 | ALDH1A1 (0.68) | ALDH1A1GAAHPGDPOLBTP53 | |
| SCHEMBL698898 | 0.73 | ALDH1A1 (0.56) | ALDH1A1GAAHPGDPOLBMAPT | |
| SCHEMBL964946 | 0.73 | DNMT1 (0.44) | ALDH1A1GAAHPGDPOLBTP53 | |
| SCHEMBL20437114 | 0.71 | ALDH1A1 (0.46) | ALDH1A1GAAPOLBCYP2D6KMT2A | |
| SCHEMBL10023265 | 0.71 | ALDH1A1 (0.36) | MAP3K5ALDH1A1GAAHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180215709-A1 | TYPE III DEIODINASE INHIBITORS AND USES THEREOF | HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) | 2018-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180215709-A1 | TYPE III DEIODINASE INHIBITORS AND USES THEREOF | TPO, DPP3, HSD17B3 | MAP3K5 1762/4885ALDH1A1 212/4885GAA 768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.